Recent advances in the development of sensitive measurements devices have allowed the identification of more than 500 different molecules in breath.
The concentrations of some of these molecules can be used as new potential biomarkers for clinical diagnosis, or for environmental exposure assessment.
Despite its considerable potential, breath samples analysis has not received enough attention. The main obstacle to the use of breath analyses for clinical applications has been the lack of established sampling protocols: inadequate attention paid while sampling breath increases variability and artifacts, alters data patterns and hinders the comparison of results.
To overcome these difficulties Loccioni humancare, in collaboration with Prof. Terence Risby, professor at Johns Hopkins University of Baltimore, has developed a new generation of Breath Sampling Devices: mouth pressure and carbon dioxide concentration are monitored and displayed in real time allowing the subject to apply a biofeedback echnique on pressure and stabilized the expiration flow to a standard value making single breath or multiple breaths sampling repeatable and reliable.